Post-Transcriptional Regulation

Single-cell transcriptomics reveal broad alterations in RNA processing in iPSC-derived neurons and glial cells from Alzheimer's Disease patients

At the second edition of IDIBELL’s RegenBell symposium I presented an update on our efforts to study transcriptomic changes in early Alzheimer’s Disease using a stem cell model. [Poster #12]

Post-transcriptional regulation in iPSC derived neural and glial cells from Alzheimer disease patients

At my first attendance of ISCO, a single-cell conference co-organized locally by the CRG in Barcelona and the BIMSB in Berlin, I presented our ongoing work to study transcriptomic changes in early Alzheimer’s Disease using a stem cell model. [Poster #63]

Quantification of transcript isoforms at the single-cell level using SCALPEL

SCALPEL, a nextflow based tool for the quantification of isoforms at single-cell resolution.

Post-transcriptional regulation in iPSC derived neural and glial cells from Alzheimer disease patients

At my first attendance of the Jornades de Bioinformàtica i Genòmica, I had the opportunity to talk about our work on transcriptomic changes in early Alzheimer’s Disease with a more technical focus. [Selected Talk; 10’ + 5']

Post-transcriptional regulation in iPSC derived neural and glial cells from Alzheimer's disease patients

I got the opportunity to present our initial results of studying transcriptomic changes in early Alzheimer’s Disease using a stem cell model at the first RegenBell symposium. [Selected Short Talk; 7’ + 3']

MiRnome-wide differential expression analyses in entorhinal cortex of Alzheimer's patients and controls highlight several novel miRNAs

At my first time attending the huge international AD/PD™ conference, I presented our work on miRNAs differentially expressed in post-mortem entorhinal cortex samples from Alzheimer’s Disease patients compared to healthy controls. [Poster #A06.G; Cell, Molecular and Systems Biology: Metabolomics, Transcriptomics, Lipidomics, Proteomics session]

Differential microRNA expression analyses across two brain regions in Alzheimer's disease

Differential expression study of microRNAs and target genes in post-mortem superior temporal gyrus and entorhinal cortex samples from 99 Alzheimer’s Disease patients and 91 aged matched control donors.

Differential microRNA expression analyses across two brain regions in Alzheimer's disease [preprint]

Preprint of differential expression study of microRNAs and target genes in post-mortem superior temporal gyrus and entorhinal cortex samples from 99 Alzheimer’s Disease patients and 91 aged matched control donors.