ScRNA-Seq

Cell type proportion and gene expression perturbations in cbp-3 RNAi in S. mediterranea

The third edition of IDIBELL’s RegenBell symposium was my first opportunity to present our recent work on understanding how smed-cbp-3 is involved in terminal differentiation during regeneration in planarians. [Poster #25]

CRISPR-engineered human GATA2 deficiency model uncovers mitotic dysfunction and premature aging in HSPCs, impairing hematopoietic fitness

Humanized mouse model study of GATA2 deficiency.

Quantification of transcript isoforms at the single-cell level using SCALPEL

SCALPEL: A Nextflow-based pipeline for isoform quantification at single-cell resolution.

Realistic scRNA-read simulation at isoform resolution using scr⁴eam

At my second attendance of the Jornades de Bioinformàtica i Genòmica, I presented scr⁴eam, a new tool I developed to simulate realistic single-cell RNA-seq reads. [Selected Talk; 7’ + 3']

Single-cell transcriptomics reveal broad alterations in RNA processing in iPSC-derived neurons and glial cells from Alzheimer's Disease patients

At the second edition of IDIBELL’s RegenBell symposium I presented an update on our efforts to study transcriptomic changes in early Alzheimer’s Disease using a stem cell model. [Poster #12]

Post-transcriptional regulation in iPSC derived neural and glial cells from Alzheimer disease patients

At my first attendance of ISCO, a single-cell conference co-organized locally by the CRG in Barcelona and the BIMSB in Berlin, I presented our ongoing work to study transcriptomic changes in early Alzheimer’s Disease using a stem cell model. [Poster #63]

Quantification of transcript isoforms at the single-cell level using SCALPEL

SCALPEL, a nextflow based tool for the quantification of isoforms at single-cell resolution.

Post-transcriptional regulation in iPSC derived neural and glial cells from Alzheimer disease patients

At my first attendance of the Jornades de Bioinformàtica i Genòmica, I had the opportunity to talk about our work on transcriptomic changes in early Alzheimer’s Disease with a more technical focus. [Selected Talk; 10’ + 5']

Post-transcriptional regulation in iPSC derived neural and glial cells from Alzheimer's disease patients

I got the opportunity to present our initial results of studying transcriptomic changes in early Alzheimer’s Disease using a stem cell model at the first RegenBell symposium. [Selected Short Talk; 7’ + 3']